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Repair or destruction—an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis
Cellular differentiation, developmental processes, and environmental factors challenge the integrity of the proteome in every eukaryotic cell. The maintenance of protein homeostasis, or proteostasis, involves folding and degradation of damaged proteins, and is essential for cellular function, organi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601288/ https://www.ncbi.nlm.nih.gov/pubmed/28699655 http://dx.doi.org/10.1002/1873-3468.12750 |