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Repair or destruction—an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis

Cellular differentiation, developmental processes, and environmental factors challenge the integrity of the proteome in every eukaryotic cell. The maintenance of protein homeostasis, or proteostasis, involves folding and degradation of damaged proteins, and is essential for cellular function, organi...

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Detalles Bibliográficos
Autores principales: Kevei, Éva, Pokrzywa, Wojciech, Hoppe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601288/
https://www.ncbi.nlm.nih.gov/pubmed/28699655
http://dx.doi.org/10.1002/1873-3468.12750