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Lipid‐like Peptides can Stabilize Integral Membrane Proteins for Biophysical and Structural Studies

A crucial bottleneck in membrane protein structural biology is the difficulty in identifying a detergent that can maintain the stability and functionality of integral membrane proteins (IMPs). Detergents are poor membrane mimics, and their common use in membrane protein crystallography may be one re...

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Detalles Bibliográficos
Autores principales: Veith, Katharina, Martinez Molledo, Maria, Almeida Hernandez, Yasser, Josts, Inokentijs, Nitsche, Julius, Löw, Christian, Tidow, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601290/
https://www.ncbi.nlm.nih.gov/pubmed/28603929
http://dx.doi.org/10.1002/cbic.201700235