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Modulation of basal cell fate during productive and transforming HPV‐16 infection is mediated by progressive E6‐driven depletion of Notch

In stratified epithelia such as the epidermis, homeostasis is maintained by the proliferation of cells in the lower epithelial layers and the concomitant loss of differentiated cells from the epithelial surface. These differentiating keratinocytes progressively stratify and form a self‐regenerating...

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Detalles Bibliográficos
Autores principales: Kranjec, Christian, Holleywood, Christina, Libert, Diane, Griffin, Heather, Mahmood, Radma, Isaacson, Erin, Doorbar, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601300/
https://www.ncbi.nlm.nih.gov/pubmed/28497579
http://dx.doi.org/10.1002/path.4917