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Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective

[Image: see text] The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane, immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of endogenous extracellular ligands and intracellular effectors. Ligand binding at the extracellular do...

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Detalles Bibliográficos
Autores principales: Bongarzone, Salvatore, Savickas, Vilius, Luzi, Federico, Gee, Antony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601361/
https://www.ncbi.nlm.nih.gov/pubmed/28482155
http://dx.doi.org/10.1021/acs.jmedchem.7b00058