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Dysregulation of Alternative Poly-adenylation as a Potential Player in Autism Spectrum Disorder

We present here the hypothesis that alternative poly-adenylation (APA) is dysregulated in the brains of individuals affected by Autism Spectrum Disorder (ASD), due to disruptions in the calcium signaling networks. APA, the process of selecting different poly-adenylation sites on the same gene, yield...

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Detalles Bibliográficos
Autores principales: Szkop, Krzysztof J., Cooke, Peter I. C., Humphries, Joanne A., Kalna, Viktoria, Moss, David S., Schuster, Eugene F., Nobeli, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601403/
https://www.ncbi.nlm.nih.gov/pubmed/28955198
http://dx.doi.org/10.3389/fnmol.2017.00279