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Co-delivery of Dual Toll-Like Receptor Agonists and Antigen in Poly(Lactic-Co-Glycolic) Acid/Polyethylenimine Cationic Hybrid Nanoparticles Promote Efficient In Vivo Immune Responses

Strategies to design delivery vehicles are critical in modern vaccine-adjuvant development. Nanoparticles (NPs) encapsulating antigen(s) and adjuvant(s) are promising vehicles to deliver antigen(s) and adjuvant(s) to antigen-presenting cells (APCs), allowing optimal immune responses against a specif...

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Detalles Bibliográficos
Autores principales: Ebrahimian, Mahboubeh, Hashemi, Maryam, Maleki, Mohsen, Hashemitabar, Gholamreza, Abnous, Khalil, Ramezani, Mohammad, Haghparast, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601407/
https://www.ncbi.nlm.nih.gov/pubmed/28955328
http://dx.doi.org/10.3389/fimmu.2017.01077