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Technique of retinal gene therapy: delivery of viral vector into the subretinal space

PURPOSE: Safe and reproducible delivery of gene therapy vector into the subretinal space is essential for successful targeting of the retinal pigment epithelium (RPE) and photoreceptors. The success of surgery is critical for the clinical efficacy of retinal gene therapy. Iatrogenic detachment of th...

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Detalles Bibliográficos
Autores principales: Xue, K, Groppe, M, Salvetti, A P, MacLaren, R E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601444/
https://www.ncbi.nlm.nih.gov/pubmed/28820183
http://dx.doi.org/10.1038/eye.2017.158