Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy

Mitochondrial health is critical for skeletal muscle function and is improved by exercise training through both mitochondrial biogenesis and removal of damaged/dysfunctional mitochondria via mitophagy. The mechanisms underlying exercise-induced mitophagy have not been fully elucidated. Here, we show...

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Detalles Bibliográficos
Autores principales: Laker, Rhianna C., Drake, Joshua C., Wilson, Rebecca J., Lira, Vitor A., Lewellen, Bevan M., Ryall, Karen A., Fisher, Carleigh C., Zhang, Mei, Saucerman, Jeffrey J., Goodyear, Laurie J., Kundu, Mondira, Yan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601463/
https://www.ncbi.nlm.nih.gov/pubmed/28916822
http://dx.doi.org/10.1038/s41467-017-00520-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601463/
https://www.ncbi.nlm.nih.gov/pubmed/28916822
http://dx.doi.org/10.1038/s41467-017-00520-9

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