Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

O-glycosylation of the Plasmodium sporozoite surface proteins CSP and TRAP was recently identified, but the role of this modification in the parasite life cycle and its relevance to vaccine design remain unclear. Here, we identify the Plasmodium protein O-fucosyltransferase (POFUT2) responsible for...

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Detalles Bibliográficos
Autores principales: Lopaticki, Sash, Yang, Annie S. P., John, Alan, Scott, Nichollas E., Lingford, James P., O’Neill, Matthew T., Erickson, Sara M., McKenzie, Nicole C., Jennison, Charlie, Whitehead, Lachlan W., Douglas, Donna N., Kneteman, Norman M., Goddard-Borger, Ethan D., Boddey, Justin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601480/
https://www.ncbi.nlm.nih.gov/pubmed/28916755
http://dx.doi.org/10.1038/s41467-017-00571-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601480/
https://www.ncbi.nlm.nih.gov/pubmed/28916755
http://dx.doi.org/10.1038/s41467-017-00571-y

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