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Trans-sialidase-based vaccine candidate protects against Trypanosoma cruzi infection, not only inducing an effector immune response but also affecting cells with regulatory/suppressor phenotype

Prophylactic and/or therapeutic vaccines have an important potential to control Trypanosoma cruzi (T. cruzi)infection. The involvement of regulatory/suppressor immune cells after an immunization treatment and T. cruzi infection has never been addressed. Here we show that a new trans-sialidase-based...

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Detalles Bibliográficos
Autores principales: Prochetto, Estefanía, Roldán, Carolina, Bontempi, Iván A., Bertona, Daiana, Peverengo, Luz, Vicco, Miguel H., Rodeles, Luz M., Pérez, Ana R., Marcipar, Iván S., Cabrera, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601629/
https://www.ncbi.nlm.nih.gov/pubmed/28938533
http://dx.doi.org/10.18632/oncotarget.18217