Targeting of the MAPK and AKT pathways in conjunctival melanoma shows potential synergy

PURPOSE: Conjunctival melanoma (CM) is a rare but lethal form of cancer. Similar to cutaneous melanoma, CM frequently carries activating mutations in BRAF and NRAS. We studied whether CM as well as conjunctival benign and premalignant melanocytic lesions express targets in the mitogen-activated prot...

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Detalles Bibliográficos
Autores principales: Cao, Jinfeng, Heijkants, Renier C., Jochemsen, Aart G., Dogrusöz, Mehmet, de Lange, Mark J., van der Velden, Pieter A., van der Burg, Sjoerd H., Jager, Martine J., Verdijk, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601630/
https://www.ncbi.nlm.nih.gov/pubmed/28938534
http://dx.doi.org/10.18632/oncotarget.10770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601630/
https://www.ncbi.nlm.nih.gov/pubmed/28938534
http://dx.doi.org/10.18632/oncotarget.10770

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