MicroRNA-128-3p regulates mitomycin C-induced DNA damage response in lung cancer cells through repressing SPTAN1

The DNA damage response is critical for maintaining genome integrity and preventing damage to DNA due to endogenous and exogenous insults. Mitomycin C (MMC), a potent DNA cross-linker, is used as a chemotherapeutic agent because it causes DNA inter-strand cross-links (DNA ICLs) in cancer cells. Whil...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Liu, Chang, Niu, Yahan, Jing, Ying, Zhang, Haiyang, Wang, Jin, Yang, Jie, Zen, Ke, Zhang, Junfeng, Zhang, Chen-Yu, Li, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601636/
https://www.ncbi.nlm.nih.gov/pubmed/28938540
http://dx.doi.org/10.18632/oncotarget.12300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601636/
https://www.ncbi.nlm.nih.gov/pubmed/28938540
http://dx.doi.org/10.18632/oncotarget.12300

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