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Sialyllactose suppresses angiogenesis by inhibiting VEGFR-2 activation, and tumor progression

The oligosaccharides in human milk have various biological functions. However, the molecular mechanism(s) underlying the anti-angiogenic action of sialylated human milk oligosaccharides (HMOs) are still unclear. Here, we show that siallylactose (SL) found in human milk can inhibit the activation of...

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Detalles Bibliográficos
Autores principales: Chung, Tae-Wook, Kim, Eun-Young, Kim, Seok-Jo, Choi, Hee-Jung, Jang, Se Bok, Kim, Keuk-Jun, Ha, Sun-Hyung, Abekura, Fukushi, Kwak, Choong-Hwan, Kim, Cheorl-Ho, Ha, Ki-Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601640/
https://www.ncbi.nlm.nih.gov/pubmed/28938544
http://dx.doi.org/10.18632/oncotarget.16192