Gemcitabine-induced heparanase promotes aggressiveness of pancreatic cancer cells via activating EGFR signaling

Pancreatic cancer (PC), characterized by aggressive local invasion and metastasis, is one of the most malignant cancers. Gemcitabine is currently used as the standard drug for the treatment of advanced and metastatic PC, but with limited efficacy. In this study, we demonstrated that gemcitabine incr...

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Detalles Bibliográficos
Autores principales: Song, Jin-Wen, Tan, Ying-Xia, Li, Su-Bo, Zhang, Shi-Kun, Wan, Lu-Ming, Ji, Shou-Ping, Zhou, Hong, Zhou, Zhi-Hang, Gong, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601663/
https://www.ncbi.nlm.nih.gov/pubmed/28938567
http://dx.doi.org/10.18632/oncotarget.16911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601663/
https://www.ncbi.nlm.nih.gov/pubmed/28938567
http://dx.doi.org/10.18632/oncotarget.16911

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