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Targeting progastrin enhances radiosensitization of colorectal cancer cells

A high percentage of advanced rectal cancers are resistant to radiation. Therefore, increasing the efficacy of radiotherapy by targeting factors involved in radioresistance seems to be an attractive strategy. Here we demonstrated that the pro-hormone progastrin (PG), known to be over-expressed in CR...

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Detalles Bibliográficos
Autores principales: Kowalski-Chauvel, Aline, Gouaze-Andersson, Valerie, Vignolle-Vidoni, Alix, Delmas, Caroline, Toulas, Christine, Cohen-Jonathan-Moyal, Elizabeth, Seva, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601677/
https://www.ncbi.nlm.nih.gov/pubmed/28938581
http://dx.doi.org/10.18632/oncotarget.17274