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Genistein up-regulates miR-20a to disrupt spermatogenesis via targeting Limk1

Genistein (GEN) is one of the isoflavones that has effect on male reproduction. However, the underlying mechanism remains unknown. miRNAs are a type of small non-coding RNAs that play important roles in spermatogenesis. We measured the GEN levels and miR-17-92 cluster expression in infertile subject...

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Detalles Bibliográficos
Autores principales: Gu, Hao, Wu, Wei, Yuan, Beilei, Tang, Qiuqin, Guo, Dan, Chen, Yiqiu, Xia, Yankai, Hu, Lingqing, Chen, Daozhen, Sha, Jiahao, Wang, Xinru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601687/
https://www.ncbi.nlm.nih.gov/pubmed/28938591
http://dx.doi.org/10.18632/oncotarget.17637