Endoplasmic reticulum stress-mediated membrane expression of CRT/ERp57 induces immunogenic apoptosis in drug-resistant endometrial cancer cells

OBJECTIVE: To investigate the role of endoplasmic reticulum (ER) stress-mediated CRT/ERp57 complex expression underlying the mechanism of resistance to doxorubicin (DOX) in endometrial carcinoma (EC) in vivo and in vitro. METHODS: The expression of CRT, ERp57, p-PERK, eIF2α, p-eIF2α in EC patients a...

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Detalles Bibliográficos
Autores principales: Xu, Qin, Chen, Chuanben, Lin, An, Xie, Yunqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601689/
https://www.ncbi.nlm.nih.gov/pubmed/28938593
http://dx.doi.org/10.18632/oncotarget.17678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601689/
https://www.ncbi.nlm.nih.gov/pubmed/28938593
http://dx.doi.org/10.18632/oncotarget.17678

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