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Multiple receptor tyrosine kinase activation related to ALK inhibitor resistance in lung cancer cells with ALK rearrangement

The activation of alternative receptor tyrosine kinases (RTKs) is known to mediate resistance to ALK inhibitors. However, the role of multiple RTK activation in resistance has yet to be determined. Two crizotinib-resistant (H3122/CR-1 and H3122/CR-2) and one TAE684-resistant (H2228/TR) cell lines we...

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Detalles Bibliográficos
Autores principales: Choi, Se Hoon, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Lee, Jung-Eun, Sung, Ki Jung, Kim, Woo Sung, Choi, Chang-Min, Rho, Jin Kyung, Lee, Jae Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601691/
https://www.ncbi.nlm.nih.gov/pubmed/28938595
http://dx.doi.org/10.18632/oncotarget.17680