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Proton pump inhibitors increase the chemosensitivity of patients with advanced colorectal cancer

Changes in pH can alter the uptake of chemotherapy drugs. Proton pump inhibitors (PPIs) may therefore increase the chemosensitivity of cancer cells and cytotoxicity of chemotherapeutic drugs by increasing their uptake. We investigated the chemosensitizing potential of PPIs in colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyu, Liu, Chun, Wang, Jiaqi, Fan, Yue, Wang, Zhenghua, Wang, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601694/
https://www.ncbi.nlm.nih.gov/pubmed/28938598
http://dx.doi.org/10.18632/oncotarget.18522