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Dickkopf-1 induces angiogenesis via VEGF receptor 2 regulation independent of the Wnt signaling pathway

Tumor angiogenesis is essential for invasive tumor growth and metastasis. Dickkopf-1 (DKK-1), an antagonist of Wnt signaling, participates in tumor development and progression. We evaluated whether DKK-1 stimulation induces angiogenesis and the endothelial–mesenchymal transition (EnMT). Human umbili...

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Detalles Bibliográficos
Autores principales: Choi, Sung Hoon, Kim, Hyemi, Lee, Hyun Gyu, Kim, Beom Kyung, Park, Jun Yong, Kim, Do Young, Ahn, Sang Hoon, Han, Kwang-Hyub, Kim, Seung Up
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601707/
https://www.ncbi.nlm.nih.gov/pubmed/28938611
http://dx.doi.org/10.18632/oncotarget.19769