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Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma

The pathological presence of tissue factor (TF) in cancer cells promotes tumor-initiated thrombosis and cancer metastasis. We found that TF is aberrantly present in large percentage of aggressive triple negative breast cancer (TNBC) and pancreatic adenocarcinoma (PaC), two most lethal forms of malig...

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Detalles Bibliográficos
Autores principales: Zhang, Xuesai, Li, Qingrou, Zhao, Hui, Ma, Lanping, Meng, Tao, Qian, Jianchang, Jin, Rui, Shen, Jingkang, Yu, Ker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601716/
https://www.ncbi.nlm.nih.gov/pubmed/28938620
http://dx.doi.org/10.18632/oncotarget.19175