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Profiling cancer-related gene mutations in oral squamous cell carcinoma from Japanese patients by targeted amplicon sequencing

Somatic mutation analysis is a standard practice in the study of human cancers to identify mutations that cause therapeutic sensitization and resistance. We performed comprehensive genomic analyses that used PCR target enrichment and next-generation sequencing on Ion Proton semiconductor sequencers....

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Detalles Bibliográficos
Autores principales: Nakagaki, Takafumi, Tamura, Miyuki, Kobashi, Kenta, Koyama, Ryota, Fukushima, Hisayo, Ohashi, Tomoko, Idogawa, Masashi, Ogi, Kazuhiro, Hiratsuka, Hiroyoshi, Tokino, Takashi, Sasaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601718/
https://www.ncbi.nlm.nih.gov/pubmed/28938622
http://dx.doi.org/10.18632/oncotarget.19262