Change from lung adenocarcinoma to small cell lung cancer as a mechanism of resistance to afatinib

We report the case of a patient affected by advanced EGFR mutation-positive lung who experienced resistance to therapy during treatment with Afatinib through the occurrence of a switch of tumor histotype to small cell lung cancer (SCLC) with features of a G3 neuroendocrine carcinoma. Unexpectedly, t...

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Detalles Bibliográficos
Autores principales: Manca, Paolo, Russano, Marco, Pantano, Francesco, Tonini, Giuseppe, Santini, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601795/
https://www.ncbi.nlm.nih.gov/pubmed/28938699
http://dx.doi.org/10.18632/oncotarget.17607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601795/
https://www.ncbi.nlm.nih.gov/pubmed/28938699
http://dx.doi.org/10.18632/oncotarget.17607

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