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Design of Multivalent Inhibitors for Preventing Cellular Uptake
Cellular entry, the first crucial step of viral infection, can be inhibited by molecules adsorbed on the virus surface. However, apart from using stronger affinity, little is known about the properties of such inhibitors that could increase their effectiveness. Our simulations showed that multivalen...
Autores principales: | Schubertová, Veronika, Martinez-Veracoechea, Francisco J., Vácha, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601900/ https://www.ncbi.nlm.nih.gov/pubmed/28916832 http://dx.doi.org/10.1038/s41598-017-11735-7 |
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