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The cancer chemotherapeutic agent paclitaxel (Taxol) reduces hippocampal neurogenesis via down-regulation of vesicular zinc

Chemotherapy-induced cognitive impairment (CICI) is increasingly recognized as a major unwanted side effect of an otherwise highly valuable life-saving technology. In part, this awareness is a result of increased cancer survival rates following chemotherapy. Altered hippocampal neurogenesis may play...

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Detalles Bibliográficos
Autores principales: Lee, Bo Eun, Choi, Bo Young, Hong, Dae Kee, Kim, Jin Hee, Lee, Song Hee, Kho, A Ra, Kim, Haesung, Choi, Hui Chul, Suh, Sang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601929/
https://www.ncbi.nlm.nih.gov/pubmed/28916767
http://dx.doi.org/10.1038/s41598-017-12054-7