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Accumulation of minor alleles and risk prediction in schizophrenia

Schizophrenia is a common neuropsychiatric disorder with a lifetime risk of 1%. Accumulation of common polygenic variations has been found to be an important risk factor. Recent studies showed a role for the enrichment of minor alleles (MAs) of SNPs in complex diseases such as Parkinson’s disease. H...

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Detalles Bibliográficos
Autores principales: He, Pei, Lei, Xiaoyun, Yuan, Dejian, Zhu, Zuobin, Huang, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601945/
https://www.ncbi.nlm.nih.gov/pubmed/28916820
http://dx.doi.org/10.1038/s41598-017-12104-0