Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a

Adam13/33 is a cell surface metalloprotease critical for cranial neural crest (CNC) cell migration. It can cleave multiple substrates including itself, fibronectin, ephrinB, cadherin-11, pcdh8 and pcdh8l (this work). Cleavage of cadherin-11 produces an extracellular fragment that promotes CNC migrat...

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Detalles Bibliográficos
Autores principales: Khedgikar, Vikram, Abbruzzese, Genevieve, Mathavan, Ketan, Szydlo, Hannah, Cousin, Helene, Alfandari, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601995/
https://www.ncbi.nlm.nih.gov/pubmed/28829038
http://dx.doi.org/10.7554/eLife.26898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601995/
https://www.ncbi.nlm.nih.gov/pubmed/28829038
http://dx.doi.org/10.7554/eLife.26898

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