The genomic landscape of human cellular circadian variation points to a novel role for the signalosome

The importance of natural gene expression variation for human behavior is undisputed, but its impact on circadian physiology remains mostly unexplored. Using umbilical cord fibroblasts, we have determined by genome-wide association how common genetic variation impacts upon cellular circadian functio...

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Detalles Bibliográficos
Autores principales: Gaspar, Ludmila, Howald, Cedric, Popadin, Konstantin, Maier, Bert, Mauvoisin, Daniel, Moriggi, Ermanno, Gutierrez-Arcelus, Maria, Falconnet, Emilie, Borel, Christelle, Kunz, Dieter, Kramer, Achim, Gachon, Frederic, Dermitzakis, Emmanouil T, Antonarakis, Stylianos E, Brown, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601996/
https://www.ncbi.nlm.nih.gov/pubmed/28869038
http://dx.doi.org/10.7554/eLife.24994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601996/
https://www.ncbi.nlm.nih.gov/pubmed/28869038
http://dx.doi.org/10.7554/eLife.24994

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