Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components

FGF2 is secreted from cells by an unconventional secretory pathway. This process is mediated by direct translocation across the plasma membrane. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully reconstituted inside-out vesicle system. FGF2 membrane...

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Detalles Bibliográficos
Autores principales: Steringer, Julia P, Lange, Sascha, Čujová, Sabína, Šachl, Radek, Poojari, Chetan, Lolicato, Fabio, Beutel, Oliver, Müller, Hans-Michael, Unger, Sebastian, Coskun, Ünal, Honigmann, Alf, Vattulainen, Ilpo, Hof, Martin, Freund, Christian, Nickel, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601999/
https://www.ncbi.nlm.nih.gov/pubmed/28722655
http://dx.doi.org/10.7554/eLife.28985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601999/
https://www.ncbi.nlm.nih.gov/pubmed/28722655
http://dx.doi.org/10.7554/eLife.28985

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