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Rapid screening and identification of ACE inhibitors in snake venoms using at-line nanofractionation LC-MS

This study presents an analytical method for the screening of snake venoms for inhibitors of the angiotensin-converting enzyme (ACE) and a strategy for their rapid identification. The method is based on an at-line nanofractionation approach, which combines liquid chromatography (LC), mass spectromet...

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Detalles Bibliográficos
Autores principales: Mladic, Marija, de Waal, Tessa, Burggraaff, Lindsey, Slagboom, Julien, Somsen, Govert W., Niessen, Wilfried M. A., Manjunatha Kini, R., Kool, Jeroen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602078/
https://www.ncbi.nlm.nih.gov/pubmed/28801827
http://dx.doi.org/10.1007/s00216-017-0531-3