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Genetic mutations in RNA-binding proteins and their roles in ALS

Mutations in genes that encode RNA-binding proteins (RBPs) have emerged as critical determinants of neurological diseases, especially motor neuron disorders such as amyotrophic lateral sclerosis (ALS). RBPs are involved in all aspects of RNA processing, controlling the life cycle of RNAs from synthe...

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Detalles Bibliográficos
Autores principales: Kapeli, Katannya, Martinez, Fernando J., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602095/
https://www.ncbi.nlm.nih.gov/pubmed/28762175
http://dx.doi.org/10.1007/s00439-017-1830-7