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Priming in a permissive type I-C CRISPR–Cas system reveals distinct dynamics of spacer acquisition and loss

CRISPR–Cas is a bacterial and archaeal adaptive immune system that uses short, invader-derived sequences termed spacers to target invasive nucleic acids. Upon recognition of previously encountered invaders, the system can stimulate secondary spacer acquisitions, a process known as primed adaptation....

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Detalles Bibliográficos
Autores principales: Rao, Chitong, Chin, Denny, Ensminger, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602111/
https://www.ncbi.nlm.nih.gov/pubmed/28724535
http://dx.doi.org/10.1261/rna.062083.117