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Priming in a permissive type I-C CRISPR–Cas system reveals distinct dynamics of spacer acquisition and loss
CRISPR–Cas is a bacterial and archaeal adaptive immune system that uses short, invader-derived sequences termed spacers to target invasive nucleic acids. Upon recognition of previously encountered invaders, the system can stimulate secondary spacer acquisitions, a process known as primed adaptation....
Autores principales: | Rao, Chitong, Chin, Denny, Ensminger, Alexander W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602111/ https://www.ncbi.nlm.nih.gov/pubmed/28724535 http://dx.doi.org/10.1261/rna.062083.117 |
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