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Ligand recognition and helical stacking formation are intimately linked in the SAM-I riboswitch regulatory mechanism
Riboswitches are noncoding mRNA elements that control gene expression by altering their structure upon metabolite binding. Although riboswitch crystal structures provide detailed information about RNA–ligand interactions, little knowledge has been gathered to understand how riboswitches modulate gen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602112/ https://www.ncbi.nlm.nih.gov/pubmed/28701520 http://dx.doi.org/10.1261/rna.061796.117 |