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Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80

Chromosome segregation requires robust interactions between the macromolecular kinetochore structure and dynamic microtubule polymers. A key outstanding question is how kinetochore-microtubule attachments are modulated to ensure that bi-oriented attachments are selectively stabilized and maintained....

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Detalles Bibliográficos
Autores principales: Kern, David M, Monda, Julie K, Su, Kuan-Chung, Wilson-Kubalek, Elizabeth M, Cheeseman, Iain M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602300/
https://www.ncbi.nlm.nih.gov/pubmed/28841134
http://dx.doi.org/10.7554/eLife.26866