Cargando…
Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80
Chromosome segregation requires robust interactions between the macromolecular kinetochore structure and dynamic microtubule polymers. A key outstanding question is how kinetochore-microtubule attachments are modulated to ensure that bi-oriented attachments are selectively stabilized and maintained....
Autores principales: | Kern, David M, Monda, Julie K, Su, Kuan-Chung, Wilson-Kubalek, Elizabeth M, Cheeseman, Iain M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602300/ https://www.ncbi.nlm.nih.gov/pubmed/28841134 http://dx.doi.org/10.7554/eLife.26866 |
Ejemplares similares
-
Aurora B kinase controls the targeting of the Astrin–SKAP complex to bioriented kinetochores
por: Schmidt, Jens C., et al.
Publicado: (2010) -
Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces
por: Volkov, Vladimir A, et al.
Publicado: (2018) -
Structural comparison of the Caenorhabditis elegans and human Ndc80 complexes bound to microtubules reveals distinct binding behavior
por: Wilson-Kubalek, Elizabeth M., et al.
Publicado: (2016) -
Orientation and structure of the Ndc80 complex on the microtubule lattice
por: Wilson-Kubalek, Elizabeth M., et al.
Publicado: (2008) -
Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin
por: Friese, Alexandra, et al.
Publicado: (2016)