Cargando…

Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged...

Descripción completa

Detalles Bibliográficos
Autores principales: Wollman, Adam JM, Shashkova, Sviatlana, Hedlund, Erik G, Friemann, Rosmarie, Hohmann, Stefan, Leake, Mark C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602325/
https://www.ncbi.nlm.nih.gov/pubmed/28841133
http://dx.doi.org/10.7554/eLife.27451