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Endogenous Isoquinoline Alkaloids Agonists of Acid-Sensing Ion Channel Type 3
Acid-sensing ion channels (ASICs) ASIC3 expressed mainly in peripheral sensory neurons play an important role in pain perception and inflammation development. In response to acidic stimuli, they can generate a unique biphasic current. At physiological pH 7.4, human ASIC3 isoform (hASIC3) is desensit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602355/ https://www.ncbi.nlm.nih.gov/pubmed/28955199 http://dx.doi.org/10.3389/fnmol.2017.00282 |