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Gastrin-releasing peptide receptor-targeted gadolinium oxide-based multifunctional nanoparticles for dual magnetic resonance/fluorescent molecular imaging of prostate cancer

Bombesin (BBN), an analog of gastrin-releasing peptide (GRP), specifically binds to GRP receptors, which are overexpressed in human prostate cancer (PC). Here, we synthesized a BBN-modified gadolinium oxide (Gd(2)O(3)) nanoprobe containing fluorescein (Gd(2)O(3)-5(6)-carboxyfluorescein [FI]-polyethy...

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Detalles Bibliográficos
Autores principales: Cui, Danting, Lu, Xiaodan, Yan, Chenggong, Liu, Xiang, Hou, Meirong, Xia, Qi, Xu, Yikai, Liu, Ruiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602459/
https://www.ncbi.nlm.nih.gov/pubmed/28979118
http://dx.doi.org/10.2147/IJN.S139246