The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive

PURPOSE: To identify novel oncogenic mutations in non-small cell lung cancer patient specimens that lack mutations in known targetable genes (“pan-negative” patients). METHODS: Comprehensive mutational analyses were performed on 1,356 lung adenocarcinoma specimens. In this cohort of patients, common...

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Detalles Bibliográficos
Autores principales: Yu, Su, Zhang, Yang, Pan, Yunjian, Cheng, Chao, Sun, Yihua, Chen, Haiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602469/
https://www.ncbi.nlm.nih.gov/pubmed/28979142
http://dx.doi.org/10.2147/OTT.S131999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602469/
https://www.ncbi.nlm.nih.gov/pubmed/28979142
http://dx.doi.org/10.2147/OTT.S131999

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