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The non-small cell lung cancer EGFR extracellular domain mutation, M277E, is oncogenic and drug-sensitive

PURPOSE: To identify novel oncogenic mutations in non-small cell lung cancer patient specimens that lack mutations in known targetable genes (“pan-negative” patients). METHODS: Comprehensive mutational analyses were performed on 1,356 lung adenocarcinoma specimens. In this cohort of patients, common...

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Detalles Bibliográficos
Autores principales:	Yu, Su, Zhang, Yang, Pan, Yunjian, Cheng, Chao, Sun, Yihua, Chen, Haiquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602469/ https://www.ncbi.nlm.nih.gov/pubmed/28979142 http://dx.doi.org/10.2147/OTT.S131999

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