Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson’s Disease

RNA interference (RNAi)-based strategies that mediate the specific knockdown of target genes by administration of small interfering RNAs (siRNAs) could be applied for treatment of presently incurable neurodegenerative diseases such as Parkinson’s disease. However, inefficient delivery of siRNA into...

Descripción completa

Detalles Bibliográficos
Autores principales: Helmschrodt, Christin, Höbel, Sabrina, Schöniger, Sandra, Bauer, Anne, Bonicelli, Jana, Gringmuth, Marieke, Fietz, Simone A., Aigner, Achim, Richter, Angelika, Richter, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602522/
https://www.ncbi.nlm.nih.gov/pubmed/29246324
http://dx.doi.org/10.1016/j.omtn.2017.08.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602522/
https://www.ncbi.nlm.nih.gov/pubmed/29246324
http://dx.doi.org/10.1016/j.omtn.2017.08.013

Ejemplares similares