Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast

Yeast frataxin homolog (Yfh1) is the orthologue of human frataxin, a mitochondrial protein whose deficiency causes Friedreich Ataxia. Yfh1 deficiency activates Aft1, a transcription factor governing iron homeostasis in yeast cells. Although the mechanisms causing this activation are not completely u...

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Detalles Bibliográficos
Autores principales: Alsina, David, Ros, Joaquim, Tamarit, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602528/
https://www.ncbi.nlm.nih.gov/pubmed/28918000
http://dx.doi.org/10.1016/j.redox.2017.09.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602528/
https://www.ncbi.nlm.nih.gov/pubmed/28918000
http://dx.doi.org/10.1016/j.redox.2017.09.001

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