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Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast

Yeast frataxin homolog (Yfh1) is the orthologue of human frataxin, a mitochondrial protein whose deficiency causes Friedreich Ataxia. Yfh1 deficiency activates Aft1, a transcription factor governing iron homeostasis in yeast cells. Although the mechanisms causing this activation are not completely u...

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Detalles Bibliográficos
Autores principales:	Alsina, David, Ros, Joaquim, Tamarit, Jordi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602528/ https://www.ncbi.nlm.nih.gov/pubmed/28918000 http://dx.doi.org/10.1016/j.redox.2017.09.001

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