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Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice

The aryl hydrocarbon receptor (AhR) is a highly conserved transcription factor that mediates a broad spectrum of species-, strain-, sex-, age-, tissue-, and cell-specific responses elicited by structurally diverse ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Dose-dependent effects o...

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Detalles Bibliográficos
Autores principales: Nault, Rance, Fader, Kelly A., Harkema, Jack R., Zacharewski, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602546/
https://www.ncbi.nlm.nih.gov/pubmed/28922406
http://dx.doi.org/10.1371/journal.pone.0184842