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Cytokine-induced killer cell delivery enhances the antitumor activity of oncolytic reovirus

Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells. The direct cytotoxic effects combined with the capacity to trigger an immune response make OV an appealing combination...

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Detalles Bibliográficos
Autores principales: Zhao, Xing, Ouyang, Weiwei, Chester, Cariad, Long, Shiqi, Wang, Nianxue, He, Zhixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602626/
https://www.ncbi.nlm.nih.gov/pubmed/28922411
http://dx.doi.org/10.1371/journal.pone.0184816