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Identifying novel transcription factors involved in the inflammatory response by using binding site motif scanning in genomic regions defined by histone acetylation

The innate immune response to pathogenic challenge is a complex, multi-staged process involving thousands of genes. While numerous transcription factors that act as master regulators of this response have been identified, the temporal complexity of gene expression changes in response to pathogen-ass...

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Detalles Bibliográficos
Autores principales: Askovich, Peter S., Ramsey, Stephen A., Diercks, Alan H., Kennedy, Kathleen A., Knijnenburg, Theo A., Aderem, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602638/
https://www.ncbi.nlm.nih.gov/pubmed/28922390
http://dx.doi.org/10.1371/journal.pone.0184850