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Host population structure impedes reversion to drug sensitivity after discontinuation of treatment

Intense use of antibiotics for the treatment of diseases such as tuberculosis, malaria, Staphylococcus aureus or gonorrhea has led to rapidly increasing population levels of drug resistance. This has generally necessitated a switch to new drugs and the discontinuation of older ones, after which resi...

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Detalles Bibliográficos
Autores principales: Liechti, Jonas I., Leventhal, Gabriel E., Bonhoeffer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602665/
https://www.ncbi.nlm.nih.gov/pubmed/28827796
http://dx.doi.org/10.1371/journal.pcbi.1005704