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Host population structure impedes reversion to drug sensitivity after discontinuation of treatment
Intense use of antibiotics for the treatment of diseases such as tuberculosis, malaria, Staphylococcus aureus or gonorrhea has led to rapidly increasing population levels of drug resistance. This has generally necessitated a switch to new drugs and the discontinuation of older ones, after which resi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602665/ https://www.ncbi.nlm.nih.gov/pubmed/28827796 http://dx.doi.org/10.1371/journal.pcbi.1005704 |