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Epigenetic clocks for gestational age: statistical and study design considerations

In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the prediction of phen...

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Detalles Bibliográficos
Autores principales: Simpkin, Andrew J., Suderman, Matthew, Howe, Laura D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602851/
https://www.ncbi.nlm.nih.gov/pubmed/28932320
http://dx.doi.org/10.1186/s13148-017-0402-y