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Macrophage activation-like syndrome: an immunological entity associated with rapid progression to death in sepsis

BACKGROUND: A subanalysis of a randomized clinical trial indicated sepsis survival benefit from interleukin (IL)-1 blockade in patients with features of the macrophage activation-like syndrome (MALS). This study aimed to investigate the frequency of MALS and to develop a biomarker of diagnosis and p...

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Detalles Bibliográficos
Autores principales: Kyriazopoulou, Evdoxia, Leventogiannis, Konstantinos, Norrby-Teglund, Anna, Dimopoulos, Georgios, Pantazi, Aikaterini, Orfanos, Stylianos E., Rovina, Nikoletta, Tsangaris, Iraklis, Gkavogianni, Theologia, Botsa, Elektra, Chassiou, Eleftheria, Kotanidou, Anastasia, Kontouli, Christina, Chaloulis, Panagiotis, Velissaris, Dimitrios, Savva, Athina, Cullberg, Jonas-Sundén, Akinosoglou, Karolina, Gogos, Charalambos, Armaganidis, Apostolos, Giamarellos-Bourboulis, Evangelos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603161/
https://www.ncbi.nlm.nih.gov/pubmed/28918754
http://dx.doi.org/10.1186/s12916-017-0930-5